Applications
High-throughput screening
High-throughput screening (HTS) is a cornerstone of modern drug discovery, enabling the rapid evaluation of large numbers of compounds, conditions, or genetic perturbations for hit identification and target validation.
However, translating assays across different formats often requires extensive re-optimization, increasing complexity, cost, and variability.
Scalable Intracellular Delivery with LumiPore®
The LumiPore® platform addresses these challenges by combining high-throughput performance with operational simplicity and scalability. Through a gentle laser-assisted photoporation mechanism, it enables efficient intracellular delivery directly in standard culture plates while preserving cell viability, functionality, and phenotype. The platform supports the delivery of a wide range of cargoes, including mRNA, plasmid DNA, CRISPR-Cas9 RNPs, siRNA, ASOs, proteins, antibodies, nanobodies, and fluorescent tracers.
LumiPore enables seamless scale-up from high-density screening formats, including 1536-well plates, to larger culture vessels without protocol redevelopment, while maintaining consistent delivery performance and reproducibility. Combined with its compatibility with automation workflows, this makes LumiPore a versatile solution for HTS campaigns, functional genomics, cell engineering, and therapeutic discovery applications.
Resources & Workflow Implementation
To learn more about implementing LumiPore in your high-throughput screening workflow, including assay development, automation, scalability, and representative application data, please refer to the sections listed below.
High-Throughput Transfection.Automation-Ready.
Seamless integration into your existing robotics workflows. No media exchange required. From R&D suspensions to clinical nanofiber structures.